Canonical Wnt Signaling Drives Myopia Development and Can Be Pharmacologically Modulated

PURPOSE: The purpose of this study was to evaluate the role of the canonical Wnt signaling in the development of the myopia. METHODS: Plasma from adult patients with myopia, myopic animal models including the adenomatous polyposis coli (APC) gene mutation mouse model, and the form deprivation (FD) i...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Liu, Zhen, Xiu, Yanghui, Qiu, Fangfang, Zhu, Zhenzhen, Zong, Rongrong, Zhou, Xiangtian, An, Jianhong, Wang, Qiongsi, Reinach, Peter S, Li, Wei, Chen, Wensheng, Liu, Zuguo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2021
Témata:
Physiology and Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288060/
https://ncbi.nlm.nih.gov/pubmed/34259818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.9.21
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