5-Fluorouracil blocks quorum-sensing of biofilm-embedded methicillin-resistant Staphylococcus aureus in mice

Antibiotic-resistant pathogens often escape antimicrobial treatment by forming protective biofilms in response to quorum-sensing communication via diffusible autoinducers. Biofilm formation by the nosocomial pathogen methicillin-resistant Staphylococcus aureus (MRSA) is triggered by the quorum-senso...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Sedlmayer, Ferdinand, Woischnig, Anne-Kathrin, Unterreiner, Vincent, Fuchs, Florian, Baeschlin, Daniel, Khanna, Nina, Fussenegger, Martin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287944/
https://ncbi.nlm.nih.gov/pubmed/33856484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab251
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