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Stereodivergent Alkyne Hydrofluorination Using Protic Tetrafluoroborates as Tunable Reagents
Vinyl fluorides play an important role in drug development as bioisosteres for peptide bonds and are found in a range of bioactive molecules. The discovery of safe, general and practical procedures to prepare vinyl fluorides from readily available precursors remains a synthetic challenge. The metal-...
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| Publicado en: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8287824/ https://ncbi.nlm.nih.gov/pubmed/32485005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006278 |
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