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p63 and p53: Collaborative Partners or Dueling Rivals?

The tumor suppressor p53 and its oncogenic sibling p63 (ΔNp63) direct opposing fates in tumor development. These paralog proteins are transcription factors that elicit their tumor suppressive and oncogenic capacity through the regulation of both shared and unique target genes. Both proteins predomin...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Woodstock, Dana L., Sammons, Morgan A., Fischer, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287303/
https://ncbi.nlm.nih.gov/pubmed/34291055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.701986
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