Electrophysiologic and Morphologic Strain Differences in a Low-Dose NaIO(3)-Induced Retinal Pigment Epithelium Damage Model

PURPOSE: We aimed to explore differences in the NaIO(3)-elicited responses of retinal pigment epithelium (RPE) and other retinal cells associated with mouse strains and dosing regimens. METHODS: One dose of NaIO(3) at 10 or 15 mg/kg was given intravenously to adult male C57BL/6J and 129/SV-E mice. C...

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Veröffentlicht in:Transl Vis Sci Technol
Hauptverfasser: Zhang, Nan, Zhang, Xian, Girardot, Preston E., Chrenek, Micah A., Sellers, Jana T., Li, Ying, Kim, Yong-Kyu, Summers, Vivian R., Ferdous, Salma, Shelton, Debresha A., Boatright, Jeffrey H., Nickerson, John M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287050/
https://ncbi.nlm.nih.gov/pubmed/34251426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.10.8.10
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