Targeting exosome-associated human antigen R attenuates fibrosis and inflammation in diabetic heart

RNA-binding proteins like human antigen R (HuR) are key regulators in post-transcriptional control of gene expression in several pathophysiological conditions. Diabetes adversely affects monocyte/macrophage biology and function. It is not known whether diabetic milieu affects cellular/exosome-HuR an...

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Veröffentlicht in:FASEB J
Hauptverfasser: Govindappa, Prem Kumar, Patil, Mallikarjun, Garikipati, Venkata Naga Srikanth, Verma, Suresh K., Saheera, Sherin, Narasimhan, Gayathri, Zhu, Wuqiang, Kishore, Raj, Zhang, Jianyi, Krishnamurthy, Prasanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286699/
https://ncbi.nlm.nih.gov/pubmed/31907992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901995R
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