LncRNA LINC00525 suppresses p21 expression via mRNA decay and triplex‐mediated changes in chromatin structure in lung adenocarcinoma

BACKGROUND: Emerging evidence suggests that long noncoding RNAs (lncRNAs) play crucial roles in various cancers. In the present study, we aim to investigate the function and molecular mechanism of an up‐regulated and survival‐associated lncRNA, LINC00525, in lung adenocarcinoma (LUAD). METHODS: The...

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Detalhes bibliográficos
Publicado no:Cancer Commun (Lond)
Main Authors: Fang, Panqi, Chen, Hao, Ma, Zhifei, Han, Chencheng, Yin, Wenda, Wang, Siwei, Zhu, Hongyu, Xia, Wenjia, Wang, Jie, Xu, Lin, Liu, Tongyan, Yin, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286138/
https://ncbi.nlm.nih.gov/pubmed/34105888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cac2.12181
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