The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion

AXL, a member of the TAM (TYRO3, AXL, MER) receptor tyrosine kinase family, and its ligand, GAS6, are implicated in oncogenesis and metastasis of many cancer types. However, the exact cellular processes activated by GAS6-AXL remain largely unexplored. Here, we identified an interactome of AXL and re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Zdżalik-Bielecka, Daria, Poświata, Agata, Kozik, Kamila, Jastrzębski, Kamil, Schink, Kay Oliver, Brewińska-Olchowik, Marta, Piwocka, Katarzyna, Stenmark, Harald, Miączyńska, Marta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285903/
https://ncbi.nlm.nih.gov/pubmed/34244439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024596118
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak