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Modeling temperature- and Cav3 subtype-dependent alterations in T-type calcium channel mediated burst firing

T-type calcium channels are important regulators of neuronal excitability. The mammalian brain expresses three T-type channel isoforms (Cav3.1, Cav3.2 and Cav3.3) with distinct biophysical properties that are critically regulated by temperature. Here, we test the effects of how temperature affects s...

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Vydáno v:Mol Brain
Hlavní autoři: Fernandez, Fernando R., Iftinca, Mircea C., Zamponi, Gerald W., Turner, Ray W.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285791/
https://ncbi.nlm.nih.gov/pubmed/34274007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00813-7
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