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Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment

Although renin-angiotensin blockade has shown beneficial outcomes in patients with diabetes, renal injury progresses in most of these patients. Therefore, there remains a need for new therapeutic targets in diabetic kidney disease. Enhancement of vasoactive peptides, such as natriuretic peptides, vi...

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Опубликовано в: :Am J Physiol Renal Physiol
Главные авторы: Myakala, Komuraiah, Jones, Bryce A., Wang, Xiaoxin X., Levi, Moshe
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285642/
https://ncbi.nlm.nih.gov/pubmed/33870733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00614.2020
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