Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice

Defective barrier function is a predisposing factor in inflammatory bowel disease (IBD) and colitis-associated cancer (CAC). Although TGFβ signaling defects have been associated with IBD and CAC, few studies have examined the relationship between TGFβ and intestinal barrier function. Here, we examin...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Marincola Smith, Paula, Choksi, Yash A., Markham, Nicholas O., Hanna, David N., Zi, Jinghuan, Weaver, Connie J., Hamaamen, Jalal A., Lewis, Keeli B., Yang, Jing, Liu, Qi, Kaji, Izumi, Means, Anna L., Beauchamp, R. Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285585/
https://ncbi.nlm.nih.gov/pubmed/33759564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00053.2021
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