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An opioid receptor-independent mechanism underlies motility dysfunction and visceral hyperalgesia in opioid-induced bowel dysfunction

Constipation and abdominal pain are commonly encountered in opioid-induced bowel dysfunction (OBD). The underlying mechanisms are incompletely understood, and treatments are not satisfactory. As patients with OBD often have fecal retention, we aimed to determine whether fecal retention plays a patho...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Lin, You-Min, Tang, Yanbo, Fu, Yu, Hegde, Shrilakshmi, Shi, Daniel W., Huang, Li-Yen M., Shi, Xuan-Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285582/
https://ncbi.nlm.nih.gov/pubmed/33908261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00400.2020
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