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Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes

Installation of fluorine into pharmaceutically relevant molecules plays a vital role in their properties of biology or medicinal chemistry. Direct difunctionalization of alkenes and 1,3-dienes to achieve fluorinated compounds through transition-metal catalysis is challenging, due to the facile β-H e...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Cheng, Xinyi, Liu, Xingchen, Wang, Shengchun, Hu, Ying, Hu, Binjing, Lei, Aiwen, Li, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285467/
https://ncbi.nlm.nih.gov/pubmed/34272392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24596-6
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