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Circulating tumor cell copy-number heterogeneity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors
Gatekeeper mutations are identified in only 50% of the cases at resistance to Anaplastic Lymphoma Kinase (ALK)-tyrosine kinase inhibitors (TKIs). Circulating tumor cells (CTCs) are relevant tools to identify additional resistance mechanisms and can be sequenced at the single-cell level. Here, we pro...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | NPJ Precis Oncol |
|---|---|
| Prif Awduron: | , , , , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group UK
2021
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8285416/ https://ncbi.nlm.nih.gov/pubmed/34272470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00203-1 |
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