The Emerging Role of Interleukin 1β (IL-1β) in Cancer Cachexia

Treatment of cancer cachexia remains an unmet need. The host-tumour interface and the resulting sequestration of the pro-inflammatory cytokine Il-1β is critical in cachexia development. Neuroinflammation mediated via IL-1β through the hypothalamic pituitary axis results in increased muscle proteolys...

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Bibliografiske detaljer
Udgivet i:Inflammation
Main Authors: Laird, Barry J., McMillan, Donald, Skipworth, Richard J. E., Fallon, Marie T., Paval, D. Robert, McNeish, Iain, Gallagher, Iain J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285330/
https://ncbi.nlm.nih.gov/pubmed/33907915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-021-01429-8
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