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Polycomb-group recruitment to a Drosophila target gene is the default state that is inhibited by a transcriptional activator

Polycomb-group (PcG) proteins are epigenetic regulators that maintain the transcriptional repression of target genes following their initial repression by transcription factors. PcG target genes are repressed in some cells, but active in others. Therefore, a mechanism must exist by which PcG protein...

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Dettagli Bibliografici
Pubblicato in:Sci Adv
Autori principali: Ghotbi, Elnaz, Ye, Piao, Ervin, Taylor, Kum, Anni, Benes, Judith, Jones, Richard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284896/
https://ncbi.nlm.nih.gov/pubmed/34272248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg1556
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