In vivo survival and differentiation of Friedreich ataxia iPSC‐derived sensory neurons transplanted in the adult dorsal root ganglia

Friedreich ataxia (FRDA) is an autosomal recessive disease characterized by degeneration of dorsal root ganglia (DRG) sensory neurons, which is due to low levels of the mitochondrial protein Frataxin. To explore cell replacement therapies as a possible approach to treat FRDA, we examined transplanta...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Viventi, Serena, Frausin, Stefano, Howden, Sara E., Lim, Shiang Y., Finol‐Urdaneta, Rocio K., McArthur, Jeffrey R., Abu‐Bonsrah, Kwaku Dad, Ng, Wayne, Ivanusic, Jason, Thompson, Lachlan, Dottori, Mirella
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2021
Assuntos:
Enabling Technologies for Cell‐Based Clinical Translation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284774/
https://ncbi.nlm.nih.gov/pubmed/33734599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.20-0334
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