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Controlled aggregation enhances immunomodulatory potential of mesenchymal stromal cell aggregates

Human mesenchymal stromal cells (MSCs) are promising candidates for cell therapy due to their ease of isolation and expansion and their ability to secrete antiapoptotic, pro‐angiogenic, and immunomodulatory factors. Three‐dimensional (3D) aggregation “self‐activates” MSCs to augment their pro‐angiog...

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Veröffentlicht in:Stem Cells Transl Med
Hauptverfasser: Xie, Angela W., Zacharias, Nicholas A., Binder, Bernard Y. K., Murphy, William L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284773/
https://ncbi.nlm.nih.gov/pubmed/33818906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0414
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