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Paradoxical regulation of allogeneic bone marrow engraftment and immune privilege by mesenchymal cells and adenosine: Differential effect of mesenchymal cell and Treg

BACKGROUND: Mesenchymal stromal cells (MSCs) exhibit immunosuppressive effects in vitro and in vivo. Therapeutic utility of MSC transfer for immune-mediated diseases has been long drawing attention. However, the role of endogenous MSCs in immune regulation in vivo has remained largely unclear. MSCs...

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Publicat a:Transplant Cell Ther
Autors principals: Kakiuchi, Miwako, Hirata, Yuichi, Robson, Simon C., Fujisaki, Joji
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284723/
https://ncbi.nlm.nih.gov/pubmed/32961376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2020.09.017
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