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Membrane proximal F-actin restricts local membrane protrusions and directs cell migration

Cell migration is driven by local membrane protrusion via directed polymerization of F-actin at the front. However, F-actin next to the plasma membrane also tethers the membrane and thus resists outgoing protrusions. Here we developed a fluorescent reporter to monitor changes in the density of membr...

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Publicado en:Science
Autores principales: Bisaria, Anjali, Hayer, Arnold, Garbett, Damien, Cohen, Daniel, Meyer, Tobias
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283920/
https://ncbi.nlm.nih.gov/pubmed/32527825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay7794
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