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Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis

BACKGROUND: Circular RNAs (circRNAs) are involved in diverse processes that drive cancer development. However, the expression landscape and mechanistic function of circRNAs in osteosarcoma (OS) remain to be studied. METHODS: Bioinformatic analysis and high-throughput RNA sequencing tools were employ...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Yang, Bingsheng, Li, Lutao, Tong, Ge, Zeng, Zhirui, Tan, Jianye, Su, Zexin, Liu, Zhengwei, Lin, Jiezhao, Gao, Wenwen, Chen, Jianping, Zeng, Sisi, Wu, Guofeng, Li, Lin, Zhu, Shuang, Liu, Qiuzhen, Lin, Lijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283840/
https://ncbi.nlm.nih.gov/pubmed/34271943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02027-0
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