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Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity
Atypical cadherin Celsr3 is critical for brain embryonic development, and its role in the postnatal cerebellum remains unknown. Using Celsr3-GFP mice, Celsr3 shows high expression in postnatal Purkinje cells (PCs). Mice with conditional knockout (cKO) of Celsr3 in postnatal PCs exhibit deficit in mo...
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| 發表在: | iScience |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8283331/ https://ncbi.nlm.nih.gov/pubmed/34308297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102812 |
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