Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity

Atypical cadherin Celsr3 is critical for brain embryonic development, and its role in the postnatal cerebellum remains unknown. Using Celsr3-GFP mice, Celsr3 shows high expression in postnatal Purkinje cells (PCs). Mice with conditional knockout (cKO) of Celsr3 in postnatal PCs exhibit deficit in mo...

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Detaylı Bibliyografya
Yayımlandı:iScience
Asıl Yazarlar: Zhou, Qinji, Qin, Jingwen, Liang, Yaying, Zhang, Wei, He, Siyuan, Tissir, Fadel, Qu, Yibo, Zhou, Libing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283331/
https://ncbi.nlm.nih.gov/pubmed/34308297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102812
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