Sigma receptor knockdown augments dysfunction and apoptosis of beta cells induced by palmitate

Sigma-1 receptor (Sig-1R) is located in the endoplasmic reticulum (ER) and clustered on the mitochondria related endoplasmic membranes, which are involved in the regulation of nervous system disease. Here, we designed Sig-1R silence MIN6 cells and studied the influence of Sig-1R silence on beta cell...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Biol Med (Maywood)
Main Authors: Ke, Mengting, He, Guangzhen, Wang, Huawei, Cheng, Siyuan, Xu, Yancheng
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2021
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283253/
https://ncbi.nlm.nih.gov/pubmed/33715527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370221997780
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