Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease

OBJECTIVE: Decreased amyloid beta (Aβ) 42 together with increased tau and phospho‐tau in cerebrospinal fluid (CSF) is indicative of Alzheimer’s disease (AD). However, the molecular pathophysiology underlying the slowly progressive cognitive decline observed in AD is not fully understood and it is no...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Bergström, Sofia, Remnestål, Julia, Yousef, Jamil, Olofsson, Jennie, Markaki, Ioanna, Carvalho, Stephanie, Corvol, Jean‐Christophe, Kultima, Kim, Kilander, Lena, Löwenmark, Malin, Ingelsson, Martin, Blennow, Kaj, Zetterberg, Henrik, Nellgård, Bengt, Brosseron, Frederic, Heneka, Michael T., Bosch, Beatriz, Sanchez‐Valle, Raquel, Månberg, Anna, Svenningsson, Per, Nilsson, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283172/
https://ncbi.nlm.nih.gov/pubmed/34129723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51402
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