Loss‐of‐function variants in K(v)11.1 cardiac channels as a biomarker for SUDEP

OBJECTIVE: To compare the frequency and impact on the channel function of KCNH2 variants in SUDEP patients with epilepsy controls comprising patients older than 50 years, a group with low SUDEP risk, and establish loss‐of‐function KCNH2 variants as predictive biomarkers of SUDEP risk. METHODS: We se...

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Bibliografske podrobnosti
izdano v:Ann Clin Transl Neurol
Main Authors: Soh, Ming S., Bagnall, Richard D., Bennett, Mark F., Bleakley, Lauren E., Mohamed Syazwan, Erlina S., Phillips, A. Marie, Chiam, Mathew D. F., McKenzie, Chaseley E., Hildebrand, Michael, Crompton, Douglas, Bahlo, Melanie, Semsarian, Christopher, Scheffer, Ingrid E., Berkovic, Samuel F., Reid, Christopher A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283159/
https://ncbi.nlm.nih.gov/pubmed/34002542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51381
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