Selectively targeting haemagglutinin antigen to chicken CD83 receptor induces faster and stronger immunity against avian influenza

The immunogenicity and protective efficacy of vaccines can be enhanced by the selective delivery of antigens to the antigen-presenting cells (APCs). In this study, H9N2 avian influenza virus haemagglutinin (HA) antigen, was targeted by fusing it to single-chain fragment variable (scFv) antibodies sp...

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Pubblicato in:NPJ Vaccines
Autori principali: Shrestha, Angita, Sadeyen, Jean-Remy, Lukosaityte, Deimante, Chang, Pengxiang, Smith, Adrian, Van Hulten, Marielle, Iqbal, Munir
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282863/
https://ncbi.nlm.nih.gov/pubmed/34267228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00350-3
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