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The Effects of Chronic Estradiol Treatment on Opioid Self-Administration in Intact Female Rats

Heroin intake decreases significantly during proestrus in normally cycling female rats, and this effect is mediated by endogenous estradiol but not endogenous progesterone. The purpose of this study was to determine whether chronic administration of exogenous estradiol decreases intake of the semi-s...

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Bibliografske podrobnosti
izdano v:Drug Alcohol Depend
Main Authors: Sharp, Jessica L., Ethridge, Sarah B., Ballard, Shannon L., Potter, Kenzie M., Schmidt, Karl T., Smith, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282761/
https://ncbi.nlm.nih.gov/pubmed/34171824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2021.108816
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