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Copper catalyzed late-stage C(sp(3))-H functionalization of nitrogen heterocycles

Nitrogen heterocycle represents a ubiquitous skeleton in natural products and drugs. Late-stage C(sp(3))-H bond functionalization of N-heterocycles with broad substrate scope remains a challenge and of particular significance to modern chemical synthesis and pharmaceutical chemistry. Here, we demons...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chang, Zhe, Huang, Jialin, Wang, Si, Chen, Geshuyi, Zhao, Heng, Wang, Rui, Zhao, Depeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282657/
https://ncbi.nlm.nih.gov/pubmed/34267229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24671-y
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