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Ginsenoside Rk1 suppresses platelet mediated thrombus formation by downregulation of granule release and α(IIb)β(3) activation

BACKGROUND AND OBJECTIVE: Synthetic ginsenoside compounds G-Rp (1,3, and 4) and natural ginsenosides in Panax ginseng 20(S)-Rg3, Rg6, F4 and Ro have inhibitory actions on human platelets. However, the inhibitory mechanism of ginsenoside Rk1 (G-Rk1) is still unclear thus, we initiated investigation o...

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Detalhes bibliográficos
Publicado no:J Ginseng Res
Main Authors: Shin, Jung-Hae, Kwon, Hyuk-Woo, Irfan, Muhammad, Rhee, Man Hee, Lee, Dong-Ha
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282495/
https://ncbi.nlm.nih.gov/pubmed/34295209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgr.2020.11.001
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