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Pharmacokinetics and Tissue Distribution of Combined Triptolide and Paeoniflorin Regimen for Percutaneous Administration in Rats Assessed by Liquid Chromatography-Tandem Mass Spectrometry

Triptolide (TP) has shown potential in rheumatoid arthritis (RA) treatment, but the narrow therapeutic window limits its clinical application. In clinical practice, the compatibility of Tripterygium wilfordii and Paeonia lactiflora is often used to attenuate the toxicity of TP, but its compatibility...

詳細記述

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書誌詳細
出版年:Evid Based Complement Alternat Med
主要な著者: Guan, Yong-mei, Shen, Qian, He, Liang-fei, Chen, Li-mei, Zang, Zhenzhong, Liu, Lili, Zhu, Wei-feng, Li-hua, Chen, Liu, Hong-ning
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282371/
https://ncbi.nlm.nih.gov/pubmed/34306159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8864273
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