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Contingency and chance erase necessity in the experimental evolution of ancestral proteins

The roles of chance, contingency, and necessity in evolution are unresolved because they have never been assessed in a single system or on timescales relevant to historical evolution. We combined ancestral protein reconstruction and a new continuous evolution technology to mutate and select proteins...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Xie, Victoria Cochran, Pu, Jinyue, Metzger, Brian PH, Thornton, Joseph W, Dickinson, Bryan C
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282340/
https://ncbi.nlm.nih.gov/pubmed/34061027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.67336
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