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Respiratory effects of low and high doses of fentanyl in control and β-arrestin 2-deficient mice

We have investigated the potential acute desensitizing role of the β arrestin 2 (β-arr2) pathway on the ventilatory depression produced by levels of fentanyl ranging from analgesic to life-threatening (0.1 to 60 mg/kg ip) in control and β-arr2-deficient nonsedated mice. Fentanyl at doses of 0.1, 0.5...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Haouzi, Philippe, McCann, Marissa, Tubbs, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282230/
https://ncbi.nlm.nih.gov/pubmed/33656934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00711.2020
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