Increased mitochondrial protein import and cardiolipin remodelling upon early mtUPR

Mitochondrial defects can cause a variety of human diseases and protective mechanisms exist to maintain mitochondrial functionality. Imbalances in mitochondrial proteostasis trigger a transcriptional program, termed mitochondrial unfolded protein response (mtUPR). However, the temporal sequence of e...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Poveda-Huertes, Daniel, Taskin, Asli Aras, Dhaouadi, Ines, Myketin, Lisa, Marada, Adinarayana, Habernig, Lukas, Büttner, Sabrina, Vögtle, F.-Nora
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282050/
https://ncbi.nlm.nih.gov/pubmed/34214073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009664
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