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Crosstalk Between DNA Methylation and Gene Mutations in Colorectal Cancer

Colorectal cancer (CRC) is often characterized by mutations and aberrant DNA methylation within the promoters of tumor suppressor genes and proto-oncogenes. The most frequent somatic mutations occur within KRAS and BRAF genes. Mutations of the KRAS gene have been detected in approximately 40% of pat...

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Publicado en:Front Oncol
Autores principales: Dobre, Maria, Salvi, Alessandro, Pelisenco, Iulia Andreea, Vasilescu, Florina, De Petro, Giuseppina, Herlea, Vlad, Milanesi, Elena
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281955/
https://ncbi.nlm.nih.gov/pubmed/34277443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.697409
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