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Human Beta-Defensin 2 and 3 Inhibit HIV-1 Replication in Macrophages
Human beta-defensins (hBDs) are broad-spectrum antimicrobial peptides, secreted by epithelial cells of the skin and mucosae, and astrocytes, which we and others have shown to inhibit HIV-1 in primary CD4(+) T cells. Although loss of CD4(+) T cells contributes to mucosal immune dysfunction, macrophag...
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| Publicado no: | Front Cell Infect Microbiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8281893/ https://ncbi.nlm.nih.gov/pubmed/34277460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.535352 |
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