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Investigation of the Recovery Stroke and ATP Hydrolysis and Changes Caused Due to the Cardiomyopathic Point Mutations in Human Cardiac β Myosin

Human cardiac β myosin undergoes the crossbridge cycle as part of the force-generating mechanism of cardiac muscle. The recovery stroke is considered one of the key steps of the kinetic cycle as it is the conformational rearrangement required to position the active site residues for hydrolysis of AT...

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Publicado en:J Phys Chem B
Main Authors: Chakraborti, Ananya, Baldo, Anthony P., Tardiff, Jil C., Schwartz, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281501/
https://ncbi.nlm.nih.gov/pubmed/34105970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.1c03144
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