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Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice

BACKGROUND: Coinciding with other chronic comorbidities, the prevalence of periodontal disease increases with aging. Mounting evidence has established that senescent cells accumulate at sites of age-related pathologies, where they promote “non-microbial” inflammation. We hypothesized that alveolar b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Periodontol
Hauptverfasser: Aquino-Martinez, Ruben, Eckhardt, Brittany A., Rowsey, Jennifer L., Fraser, Daniel G., Khosla, Sundeep, Farr, Joshua N., Monroe, David G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281492/
https://ncbi.nlm.nih.gov/pubmed/33341947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JPER.20-0529
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