Downregulating lncRNA NEAT1 induces proliferation and represses apoptosis of ovarian granulosa cells in polycystic ovary syndrome via microRNA-381/IGF1 axis

OBJECTIVE: Researchers have revealed the combined functions of long noncoding RNAs (lncRNAs) and microRNA (miRNAs) in polycystic ovary syndrome (PCOS). This study aimed to understand the role of nuclear-enriched abundant transcript 1 (NEAT1) and miR-381 involving insulin-like growth factor 1 (IGF1)...

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Veröffentlicht in:J Biomed Sci
Hauptverfasser: Zhen, Jingran, Li, Jiangli, Li, Xia, Wang, Xue, Xiao, Yaling, Sun, Zhengyi, Yu, Qi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281489/
https://ncbi.nlm.nih.gov/pubmed/34266430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-021-00749-z
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