Annexin A1 Tripeptide Mimetic Increases Sirtuin-3 and Augments Mitochondrial Function to Limit Ischemic Kidney Injury

Background: Acute kidney injury (AKI) is one of the most common organ failures following surgery. We have developed a tripeptide mimetic (ANXA1sp) of the parent annexin A1 molecule that shows promise as an organ protectant limiting cellular stress; however, its potential as a kidney protective agent...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Suliman, Hagir, Ma, Qing, Zhang, Zhiquan, Ren, Jiafa, Morris, Benjamin T., Crowley, Steven D., Ulloa, Luis, Privratsky, Jamie R.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281307/
https://ncbi.nlm.nih.gov/pubmed/34276404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.683098
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