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Precursor Abundance Influences Divergent Antigen-Specific CD8(+) T Cell Responses after Yersinia pseudotuberculosis Foodborne Infection

Primary infection of C57BL/6 mice with the bacterial pathogen Yersinia pseudotuberculosis elicits an unusually large H-2K(b)-restricted CD8(+) T cell response to the endogenous and protective bacterial epitope YopE(69–77). To better understand the basis for this large response, the model OVA(257–264...

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Pubblicato in:Infect Immun
Autori principali: Zhang, Yue, Qiu, Zhijuan, Sheridan, Brian S., Bliska, James B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281229/
https://ncbi.nlm.nih.gov/pubmed/34031132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00265-21
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