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The Rcs Stress Response System Regulator GumB Modulates Serratia marcescens-Induced Inflammation and Bacterial Proliferation in a Rabbit Keratitis Model and Cytotoxicity In Vitro

In this study, we tested the hypothesis that the conserved bacterial IgaA-family protein, GumB, mediates microbial pathogenesis associated with Serratia marcescens ocular infections through regulation of the Rcs stress response system. The role of the Rcs system and bacterial stress response systems...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Romanowski, Eric G., Stella, Nicholas A., Romanowski, John E., Yates, Kathleen A., Dhaliwal, Deepinder K., St. Leger, Anthony J., Shanks, Robert M. Q.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281226/
https://ncbi.nlm.nih.gov/pubmed/33820815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00111-21
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