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Imidazolium labelling permits the sensitive mass-spectrometric detection of N-glycosides directly from serum
A novel imidazolium derivative (GITag) shows superior ionisation and consequently allows increased mass spectrometric detection capabilities of oligosaccharides and N-glycans. Here we demonstrate that human serum samples can be directly labelled by GITag on a MALDI target plate, abrogating prevalent...
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| Udgivet i: | Chem Commun (Camb) |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society of Chemistry
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8280963/ https://ncbi.nlm.nih.gov/pubmed/34159978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1cc02100a |
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