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Structural mechanism for modulation of functional amyloid and biofilm formation by Staphylococcal Bap protein switch

The Staphylococcal Bap proteins sense environmental signals (such as pH, [Ca(2+)]) to build amyloid scaffold biofilm matrices via unknown mechanisms. We here report the crystal structure of the aggregation‐prone region of Staphylococcus aureus Bap which adopts a dumbbell‐shaped fold. The middle modu...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Ma, Junfeng, Cheng, Xiang, Xu, Zhonghe, Zhang, Yikan, Valle, Jaione, Fan, Shilong, Zuo, Xiaobing, Lasa, Iñigo, Fang, Xianyang
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280801/
https://ncbi.nlm.nih.gov/pubmed/34046916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020107500
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