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Molecular Dynamics Study of Conformational Changes of Tankyrase 2 Binding Subsites upon Ligand Binding

[Image: see text] The interactions between proteins and ligands are involved in various biological functions. While experimental structures provide key static structural information of ligand-unbound and ligand-bound proteins, dynamic information is often insufficient for understanding the detailed...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Hirano, Yoshinori, Okimoto, Noriaki, Fujita, Shigeo, Taiji, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280666/
https://ncbi.nlm.nih.gov/pubmed/34278146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c02159
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