Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global crisis, urgently necessitating the development of safe, efficacious, convenient-to-store, and low-cost vaccine options. A major challenge is that the receptor-binding domain (RBD)-only vaccine fails to trigger long-last...

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Udgivet i:Cell Res
Main Authors: Sun, Shiyu, Cai, Yueqi, Song, Tian-Zhang, Pu, Yang, Cheng, Lin, Xu, Hairong, Sun, Jing, Meng, Chaoyang, Lin, Yifan, Huang, Haibin, Zhao, Fang, Zhang, Silin, Gao, Yu, Han, Jian-Bao, Feng, Xiao-Li, Yu, Dan-Dan, Zhu, Yalan, Gao, Pu, Tang, Haidong, Zhao, Jincun, Zhang, Zheng, Yang, Jiaming, Hu, Zhenxiang, Fu, Yang-Xin, Zheng, Yong-Tang, Peng, Hua
Format: Artigo
Sprog:Inglês
Udgivet: Springer Singapore 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280646/
https://ncbi.nlm.nih.gov/pubmed/34267349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-021-00531-8
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