CPEB3-dowregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice

Susceptibility or resilience to posttraumatic stress disorder (PTSD) depends on one’s ability to appropriately adjust synaptic plasticity for coping with the traumatic experience. Activity-regulated mRNA translation synthesizes plasticity-related proteins to support long-term synaptic changes and me...

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Gepubliceerd in:Neuropsychopharmacology
Hoofdauteurs: Lu, Wen-Hsin, Chao, Hsu-Wen, Lin, Pei-Yi, Lin, Shu-Hui, Liu, Tzu-Hsien, Chen, Hao-Wen, Huang, Yi-Shuian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280193/
https://ncbi.nlm.nih.gov/pubmed/33941859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-021-01017-2
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