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Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses

The rational development of norovirus vaccine candidates requires a deep understanding of the antigenic diversity and mechanisms of neutralization of the virus. Here, we isolate and characterize a panel of broadly cross-reactive naturally occurring human monoclonal IgMs, IgAs and IgGs reactive with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Alvarado, Gabriela, Salmen, Wilhelm, Ettayebi, Khalil, Hu, Liya, Sankaran, Banumathi, Estes, Mary K., Venkataram Prasad, B. V., Crowe, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280134/
https://ncbi.nlm.nih.gov/pubmed/34262046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24649-w
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