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Cardiac Glycoside Ouabain Exerts Anticancer Activity via Downregulation of STAT3

Cardiac glycosides are plant-derived steroid-like compounds which have been used for the treatment of cardiovascular diseases. Ouabain, a cardiotonic steroid and specific Na(+)/K(+)-ATPase inhibitor, has been rediscovered for its potential use in the treatment of cancer. However, the cellular target...

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Podrobná bibliografie
Vydáno v:Front Oncol
Hlavní autoři: Du, Jie, Jiang, Lijun, Chen, Fuqiang, Hu, Huantao, Zhou, Meijuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279743/
https://ncbi.nlm.nih.gov/pubmed/34277430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.684316
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