TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies

Multiple myeloma (MM), a terminally differentiated B cell malignancy, remains difficult to cure. Understanding the molecular mechanisms underlying the progression of MM may identify therapeutic targets and lead to a fundamental shift in treatment of the disease. Deubiquitination, like ubiquitination...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Li, Can, Xia, Jiliang, Franqui-Machin, Reinaldo, Chen, Fangping, He, Yanjuan, Ashby, Timothy Cody, Teng, Feixiang, Xu, Hongwei, Liu, Dingxiao, Gai, Dongzheng, Johnson, Sarah K., van Rhee, Frits, Janz, Siegfried, Shaughnessy, John D., Tricot, Guido, Frech, Ivana, Zhan, Fenghuang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279583/
https://ncbi.nlm.nih.gov/pubmed/34061780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI146893
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