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Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells

Tissue-resident memory T cells (T(RMs)) can profoundly enhance mucosal immunity, but parameters governing T(RM) induction by vaccination remain poorly understood. Here we describe an approach exploiting natural albumin transport across the airway epithelium to enhance mucosal T(RM) generation by vac...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Immunol
Prif Awduron: Rakhra, Kavya, Abraham, Wuhbet, Wang, Chensu, Moynihan, Kelly D., Li, Na, Donahue, Nathan, Baldeon, Alexis D., Irvine, Darrell J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279396/
https://ncbi.nlm.nih.gov/pubmed/33741657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abd8003
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